GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs17030613 | 1 | rs17030651 | chr1:113239382 | ST7L | chr1:113066142-113162405:- | 0.4 | 5.9 | 8.12E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs17036023 | 1 | rs17036023 | chr1:117129711 | VANGL1 | chr1:116184574-116240845:+ | 0.5 | 4.08 | 5.41E-5 | Asthma (childhood onset) |
| BLCA | cis | rs9815354 | 1 | rs17061431 | chr3:41792655 | ULK4 | chr3:41288091-42003660:- | 0.61 | 9.43 | 4.0E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs17062109 | chr3:41810364 | ULK4 | chr3:41288091-42003660:- | 0.61 | 9.5 | 2.39E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs17063584 | chr3:41861463 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.78 | 2.63E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs17063599 | chr3:41861676 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.63 | 8.26E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs17063649 | chr3:41863406 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.63 | 8.26E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs17064124 | chr3:41890803 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.91 | 9.53E-21 | Diastolic blood pressure |
| BLCA | cis | rs2275426 | 1 | rs1707304 | chr1:46598269 | CCDC163P | chr1:45960581-45965646:- | -0.34 | -6.37 | 5.54E-10 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs1707321 | chr1:46505309 | CCDC163P | chr1:45960581-45965646:- | -0.36 | -6.84 | 3.15E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs1707335 | chr1:46571921 | CCDC163P | chr1:45960581-45965646:- | -0.33 | -6.21 | 1.42E-9 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs1707336 | chr1:46493460 | CCDC163P | chr1:45960581-45965646:- | -0.34 | -6.43 | 3.9E-10 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs1707340 | chr1:46514942 | CCDC163P | chr1:45960581-45965646:- | -0.33 | -6.25 | 1.11E-9 | Body mass index |
| BLCA | cis | rs2239557 | 1 | rs17096228 | chr14:74558669 | LIN52 | chr14:74551656-74667117:+ | 0.35 | 7.97 | 1.8E-14 | Common traits (Other) |
| BLCA | cis | rs7956611 | 1 | rs17102580 | chr12:66902873 | CAND1 | chr12:67663061-67708388:+ | 0.23 | 4.42 | 1.27E-5 | Age of smoking initiation |